Defoamer for Fermentation | Foam Control for Molasses, Ethanol, Citric Acid & Vitamin Bioprocess
Select a fermentation antifoam for your medium, operating temperature, pH, aeration and downstream separation process. INVINO offers silicone and non-silicone options for evaluation in molasses, ethanol, citric acid, vitamin and amino acid processes. Confirm foam suppression, culture performance, oxygen transfer and product recovery under your actual process conditions before scale-up.
Sterilization stability, membrane compatibility and effects on oxygen transfer are grade- and process-dependent. Test the selected antifoam through the intended sterilization cycle and assess filtration performance and fermentation results at the proposed dose. Request the grade-specific technical data sheet before starting trials.
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INVINO® Fermentation System Defoamer Products
| PRODUCT CODE | TYPE | ACTIVE SOLID (%) | Application / Best For | TECHNICAL FILES |
|---|---|---|---|---|
| INVINO-4000B | Polyether Ester | 100.0 | Optimized for sugarcane/beet molasses ethanol fermentation, yeast cultivation, and high-gravity fuel alcohol. | DOWNLOAD |
| INVINO-103 | Alkylene Oxide Block Copolymer | 100.0 | Calibrated for amino acids, MSG / glutamic acid, lysine, and organic acid fermentation. | DOWNLOAD |
| INVINO-103B | Block Polyether | 100.0 | Engineered for high-purity deep-culture systems, vitamin fermentation (Vitamin C, B12), and continuous citric acid tanks. | DOWNLOAD |
| INVINO-7030D | Silicone Emulsion | 30.0±1.0 | High-dispersion compound for waste yeast mash, food-regulated processing, and bulk molasses distillation. | DOWNLOAD |
Fermentation Defoamer Applications
The high viscosity and solids in molasses, corn, and grain ethanol mashes trap foam and make it hard to collapse. Our silicone-free polyethers penetrate viscous broth quickly and keep the foam layer down at high temperature — freeing up working volume and protecting fermentation yield.
Submerged production of citric acid, vitamins (C, B12), amino acids (glutamic acid / MSG, lysine), and yeast extract runs in deep tanks where protein-rich broth builds stubborn foam. Evaluate the selected polyether grade for culture performance, sterilization stability and downstream membrane compatibility in the actual medium.
Fermentation Defoaming: Technical FAQ
Q: Will the defoamer affect the Oxygen Transfer Rate (OTR / KLa)?
A: Effects on oxygen transfer depend on antifoam chemistry, dose, broth composition and operating conditions. Measure oxygen transfer or a process-relevant indicator together with culture performance and foam control before scale-up.
Q: Is the defoamer stable during high-temperature sterilization (Autoclave / SIP)?
A: Sterilization stability is grade- and process-dependent. Follow the selected grade's technical guidance and test it through your intended autoclave or SIP temperature, pressure and holding time.
Q: Does this product affect downstream membrane filtration (UF/RO)?
A: Membrane compatibility depends on the antifoam grade, dose, broth and separation process. Evaluate flux, fouling, cleaning and product recovery with the actual UF/RO system before production use.
Q: How should I add the defoamer to the fermenter?
A: Follow a grade-specific dosing procedure validated for your fermenter. Establish the dose, addition point and timing through trials, then confirm that any foam-sensor and metering-pump controls respond appropriately.
Technical Guide for Fermentation Foam Control
For process-specific operating parameters in ethanol production, review our molasses fermentation foam-control guide.
Request Your Fermentation Defoamer Solution
Standard Protocol for Bioprocess Sample Dispatch
System Parameter Submission
Share your microbial strain, operating temperature, aeration rate, and downstream separation setup (UF/RO).
Free Lab Test (121°C + Strain Check)
Send us your broth and our fermentation lab runs a 121°C autoclave simulation and strain-compatibility check, then compiles a matched profile — free of charge.
Free Sample Dispatch
Free samples (100–500 g) ship via air express for real tank trials. No MOQ at sample stage; buyer covers freight, refunded on the first bulk order.
